Acne starts during puberty when your body activates your sebum glands to secrete an oily substance that when on the surface of the skin it soothes it and shields your skin from infection by microbes that thrive there permanently. If sebum does not outflow freely through the sebum canals to the surface it produces several skin injuries that trigger an inflammatory reaction and the sebum accumulated there becomes a rich feeding ground for the growth of microbes.

Such infections place heavy demands upon the skin's components. Areas with recurrent acne infections due to moderate or severe acne commonly develop deficiencies of essential ingredients, impairing the skin's ability to defend itself and heal efficiently.

Acne infections destroy collagen and elastin fibers, interrupt the microvascular network and harm and kill cells. When healing happens, usually after a long time if a proper acne treatment has not be applied, a scar is left in the skin. The healthy functional tissue (skin) is replaced by connective tissue (scar).

Natural Ingredient Known to Treat Acne

Bacteria have survived for millions of years by developing resistance to new stressors including natural antibiotics like penicillin. What really occurs is that the bacteria, with a high rate of mutation, ends up modifying one or more of its enzymes that are used to destroy the link between a target protein and the antibiotic. As a result, the antibiotic does not have effect.

But this system fails when the attacker punches holes in the cell membrane, as peptide antibiotics do. To protect itself, the bacterium would have to modify the entire composition of the cell membrane. And to change the composition of a membrane would mean modifying most of the enzymes that are responsible for making the complex membrane in the first place.

Peptide antibiotics react within minutes helping treat acne instantly. Part of the reason for this rapid response is how the peptide acts on the cell membrane. But to kill a cell, the peptide must also quickly find the bacterial membrane. How does this occur? The answer lies in the structure of the cellular membrane.

The plasma membrane of eukaryotic cells is very different from the membrane of a prokaryotic cell. Eukaryotic cell membranes are constructed of a phospholipid bilayer and cholesterol. Consequently, these membranes have a low negative electrical charge. On the other hand, a bacterial membrane is composed by fats and sugars. This difference in composition means that bacteria have a high negative electrical charge that quickly attracts the peptide antibiotics.

Peptide antibiotics are effective. In one clinical trial for the treatment of meningitis, a sickness that affects 3,000 children a year, a peptide antibiotic not only killed the bacterium which mades the toxin, but it also bound to the toxin preventing the harm the endotoxin produces. But bringing a drug to clinical trial is time consuming and expensive. It takes $300 million to bring a drug to market. This price covers every thing from finding, identification, production and clinical trials. This process can also take 10 or more years to accomplish.